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The crash occurred near Pittstown Road and Baker Road in Franklin Township shortly before 5:30 p.m., according to the Quakertown Fire Company.
Emergency crews responded within five minutes and found a trauma patient requiring transportation, the department said.
A NorthSTAR medical helicopter landed at Sky Manor Airport to take the victim to a nearby hospital for treatment of traumatic injuries.
The scene was cleared within an hour, the department said.
The cause of the crash was not immediately clear.
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